What is CJC-1295 (No DAC)?
CJC-1295 (No DAC) is a synthetic analog of growth hormone–releasing hormone (GHRH) intended for laboratory investigation of receptor-binding characteristics and associated intracellular signaling mechanisms. The “No DAC” form refers to its shorter research half-life profile in controlled experimental environments.Mechanism of Research Interest
CJC-1295 (No DAC) is examined in vitro and in non-clinical models to evaluate interaction with GHRH receptor systems and downstream signaling pathways. Research may include analysis of receptor affinity, pathway activation patterns, and compound stability under laboratory conditions.Why Researchers Study CJC-1295 (No DAC)
- To analyze GHRH receptor-binding characteristics in laboratory assays
- To evaluate intracellular signaling responses in controlled experimental models
- To examine structural and biochemical properties under research conditions
Research Background
CJC-1295 without Drug Affinity Complex (Mod GRF 1-29) (CJC-1295 (NO DAC)) is a synthetic analog of growth hormone-releasing hormone (GHRH), also referred to as Modified GRF (1-29). Unlike the DAC variant, this version does not include the Drug Affinity Complex and has been studied for its shorter-duration GHRH receptor interactions in laboratory research.
Laboratory Research Areas
In published scientific literature, CJC-1295 (NO DAC) has been explored in the following research contexts:
- GHRH receptor binding and signal transduction in cell-based assays
- Comparative pharmacokinetics between DAC and non-DAC GHRH analogs
- Pulsatile versus sustained receptor activation in preclinical research
- Peptide stability and degradation profiling
Product Specifications
- Form: Lyophilized powder
- Storage: Store at -20°C, protect from light
- Brand: Alpha Peptides
- Purity: ≥98% (verified by HPLC)
Quality & Testing Transparency
Every batch of CJC-1295 (NO DAC) supplied by Alpha Peptides is accompanied by third-party analytical testing documentation. Our Certificates of Analysis (COAs) verify compound identity via mass spectrometry and purity via HPLC analysis. View our published testing records on the Certificates of Analysis page.
Published Research References
The following peer-reviewed publications provide context for the scientific investigation of this compound. These references are provided for informational purposes only.
- Jette L, Leger R, Thibaudeau K, et al. (2005). “Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats.” Endocrinology, 146(7), 3052-3058. PMID: 15817669
- Alba M, Fintini D, Sagazio A, et al. (2006). “Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse.” American Journal of Physiology, 291(6), E1290-E1294. PMID: 16822960
- Teichman SL, Neale A, Lawrence B, et al. (2006). “Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295.” Journal of Clinical Endocrinology & Metabolism, 91(3), 799-805. PMID: 16352683
Related Research Compounds
Researchers investigating this compound may also be interested in the following related research peptides:
| Attributes | Value |
|---|---|
| Weight | |
| Dimensions | |
| Dosage |
5 MG |
| Brand |
Alpha Peptides |
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