What is CJC-1295 (With DAC)?
CJC-1295 (With DAC) is a synthetic analog of growth hormone–releasing hormone (GHRH) intended for laboratory investigation of receptor-binding characteristics and associated intracellular signaling mechanisms. The inclusion of DAC (Drug Affinity Complex) is studied for its effect on extending compound stability and research half-life under controlled experimental conditions.Mechanism of Research Interest
CJC-1295 (With DAC) is examined in vitro and in non-clinical models to evaluate interaction with GHRH receptor systems and downstream signaling pathways. The DAC component is analyzed for its role in altering peptide binding behavior and resistance to degradation in laboratory settings.Why Researchers Study CJC-1295 (With DAC)
- To analyze receptor-binding affinity in controlled laboratory assays
- To evaluate intracellular signaling responses in experimental models
- To investigate structural stability and compound behavior under research conditions
Published Research References
The following peer-reviewed publications provide context for the scientific investigation of this compound. These references are provided for informational purposes only.
- Teichman SL, Neale A, Lawrence B, et al. (2006). “Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults.” Journal of Clinical Endocrinology & Metabolism, 91(3), 799-805. PMID: 16352683
- Alba M, Fintini D, Sagazio A, et al. (2006). “Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse.” American Journal of Physiology, 291(6), E1290-E1294. PMID: 16822960
- Jette L, Leger R, Thibaudeau K, et al. (2005). “Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats.” Endocrinology, 146(7), 3052-3058. PMID: 15817669
Research Background
CJC-1295 with Drug Affinity Complex (CJC-1295 (WITH DAC)) is a synthetic analog of growth hormone-releasing hormone (GHRH) modified with a Drug Affinity Complex (DAC) that facilitates albumin binding. It has been examined in laboratory research for its interaction with GHRH receptor signaling and its extended half-life characteristics.
Laboratory Research Areas
In published scientific literature, CJC-1295 (WITH DAC) has been explored in the following research contexts:
- GHRH receptor binding and activation in in vitro assays
- Albumin-binding kinetics and extended half-life characterization
- Growth hormone axis signaling in preclinical models
- Peptide-DAC conjugation stability and structural analysis
Product Specifications
- Form: Lyophilized powder
- Storage: Store at -20°C, protect from light
- Brand: Alpha Peptides
- Purity: ≥98% (verified by HPLC)
Quality & Testing Transparency
Every batch of CJC-1295 (WITH DAC) supplied by Alpha Peptides is accompanied by third-party analytical testing documentation. Our Certificates of Analysis (COAs) verify compound identity via mass spectrometry and purity via HPLC analysis. View our published testing records on the Certificates of Analysis page.
Related Research Compounds
Researchers investigating this compound may also be interested in the following related research peptides:
| Attributes | Value |
|---|---|
| Weight | |
| Dimensions | |
| Dosage |
5 MG |
| Brand |
Alpha Peptides |
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