What is Melanotan II?
Melanotan II (MT-2) is a synthetic analog of alpha-melanocyte–stimulating hormone (α-MSH). It is intended for laboratory investigation of melanocortin receptor interaction and associated intracellular signaling pathways in controlled research environments.Mechanism of Research Interest
Melanotan II is examined in vitro and in non-clinical models for its interaction with melanocortin receptors, including MC1R and MC4R. Research may include evaluation of receptor-binding characteristics, signal transduction activity, and peptide stability under experimental conditions.Why Researchers Study Melanotan II
- To analyze melanocortin receptor-binding activity in laboratory assays
- To evaluate intracellular signaling responses in controlled experimental models
- To examine structural and biochemical characteristics under research conditions
Research Background
Melanotan II (Melanotan II) is a synthetic cyclic peptide analog of alpha-melanocyte stimulating hormone (alpha-MSH). It has been investigated in laboratory research for its interaction with melanocortin receptor subtypes (MC1R-MC5R) and associated downstream signaling in preclinical models.
Laboratory Research Areas
In published scientific literature, Melanotan II has been explored in the following research contexts:
- Melanocortin receptor subtype binding and selectivity profiling
- MC1R-MC5R activation and downstream signaling characterization
- Cyclic peptide structure-activity relationship studies
- Receptor desensitization and internalization kinetics
Product Specifications
- Molecular Weight: ~1024 Da
- Form: Lyophilized powder
- Storage: Store at -20°C, protect from light
- Brand: Alpha Peptides
- Purity: ≥98% (verified by HPLC)
Quality & Testing Transparency
Every batch of Melanotan II supplied by Alpha Peptides is accompanied by third-party analytical testing documentation. Our Certificates of Analysis (COAs) verify compound identity via mass spectrometry and purity via HPLC analysis. View our published testing records on the Certificates of Analysis page.
Published Research References
The following peer-reviewed publications provide context for the scientific investigation of this compound. These references are provided for informational purposes only.
- Ter Laak MP, Brakkee JH, Adan RAH, et al. (2003). “The potent melanocortin receptor agonist melanotan-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat.” European Journal of Pharmacology, 462(1-3), 179-183. PMID: 12591111
- Chen AS, Metzger JM, Trumbauer ME, et al. (2000). “Role of the melanocortin-4 receptor in metabolic rate and food intake in mice.” Transgenic Research, 9(2), 145-154. PMID: 10951699
Related Research Compounds
Researchers investigating this compound may also be interested in the following related research peptides:
| Attributes | Value |
|---|---|
| Weight | |
| Dimensions | |
| Dosage |
10 MG, 5 MG |
| Brand |
Alpha Peptides |
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