What is MOTS-C?
MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondrial-derived peptide (MDP) that has drawn attention in preclinical research for its role in regulating cellular energy, metabolism, and insulin sensitivity. Unlike traditional peptides synthesized in the nucleus, MOTS-C originates from mitochondrial DNA, representing a unique class of signaling molecules.
Mechanism of Interest
MOTS-C appears to influence metabolic pathways related to AMPK activation, glucose regulation, and fatty acid oxidation. These properties have positioned it as a potential candidate in aging, exercise performance, and metabolic research models.
Why Researchers Study MOTS-C
- Studied for its role in improving insulin sensitivity and mitochondrial function
- Explored in models of metabolic disorders and fatigue resistance
- Considered in aging and longevity research due to its unique mitochondrial origin
Note: This product is provided for laboratory research purposes only. It is not intended for human consumption, medical, diagnostic, or therapeutic use.





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