What is Ipamorelin?
Ipamorelin is a synthetic peptide classified as a growth hormone secretagogue (GHS) receptor–targeting research compound. It is studied in controlled laboratory environments for its interaction with ghrelin receptor (GHS-R1a) binding sites and associated intracellular signaling pathways.Mechanism of Research Interest
Ipamorelin is examined in vitro and in non-clinical research models to evaluate receptor-binding characteristics, signal transduction activity, and structure–activity relationships within GHS receptor systems. Research may include analysis of pathway activation and compound stability under experimental conditions.Why Researchers Study Ipamorelin
- To analyze receptor-binding affinity in laboratory assays
- To evaluate intracellular signaling responses in controlled models
- To investigate structural and biochemical properties under research conditions
Research Background
Ipamorelin (IPAMORELIN) is a synthetic pentapeptide growth hormone secretagogue that selectively binds to the ghrelin/growth hormone secretagogue receptor (GHS-R). It has been examined in laboratory research for its selective GHS-R interaction profile and growth hormone axis signaling.
Laboratory Research Areas
In published scientific literature, IPAMORELIN has been explored in the following research contexts:
- GHS-R binding selectivity and activation in receptor assays
- Growth hormone secretagogue signaling pathway characterization
- Selectivity profiling compared to other GHS-R ligands
- Peptide structure-activity relationship studies
Product Specifications
- Sequence Length: 5 amino acids
- Molecular Weight: ~711 Da
- Form: Lyophilized powder
- Storage: Store at -20°C, protect from light
- Brand: Alpha Peptides
- Purity: ≥98% (verified by HPLC)
Quality & Testing Transparency
Every batch of IPAMORELIN supplied by Alpha Peptides is accompanied by third-party analytical testing documentation. Our Certificates of Analysis (COAs) verify compound identity via mass spectrometry and purity via HPLC analysis. View our published testing records on the Certificates of Analysis page.
Published Research References
The following peer-reviewed publications provide context for the scientific investigation of this compound. These references are provided for informational purposes only.
- Raun K, Hansen BS, Johansen NL, et al. (1998). “Ipamorelin, the first selective growth hormone secretagogue.” European Journal of Endocrinology, 139(5), 552-561. PMID: 9849822
- Andersen NB, Malmlof K, Johansen PB, et al. (2001). “The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced decrease in bone formation of adult rats.” Growth Hormone & IGF Research, 11(5), 266-272. PMID: 11735244
- Johansen PB, Nowak J, Skjaerbaek C, et al. (1999). “Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats.” Growth Hormone & IGF Research, 9(2), 106-113. PMID: 10373343
Related Research Compounds
Researchers investigating this compound may also be interested in the following related research peptides:
| Attributes | Value |
|---|---|
| Weight | |
| Dimensions | |
| Dosage |
10 MG, 5 MG |
| Brand |
Alpha Peptides |
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